How to Beat Bio-Weapon Brutal Mode in Plague Inc.

Beating the Bio-Weapon Brutal Mode in Plague Inc. can be a challenge, but with the right strategy and tactics, it is definitely possible. Here are some tips to help you succeed:

1. Start in a country with a high population and a busy airport, such as China or India.

2. Focus on evolving transmission first, such as Air and Water, to quickly spread the disease across the globe.

3. Once the disease has spread, focus on evolving the more lethal symptoms to increase the death rate and severity of the disease.

4. Be sure to also evolve drug resistance to prevent any potential cure efforts from slowing down your progress.

5. Use your DNA points wisely and strategically, investing in the most effective and impactful upgrades.

6. Stay aware of the world events, such as research efforts or border closings, and adapt your strategy accordingly.

7. Use the special abilities of the Bio-Weapon, such as its ability to infect and kill faster at the cost of increased visibility, to your advantage.

8. Keep a low profile as long as possible, and only become more visible and aggressive once the disease has spread to a significant degree.

9. Keep an eye on the cure progress and target countries that are leading the charge in research, and either slow their progress or infect them more heavily.

10. Be patient, as the Bio-Weapon can be difficult to control, and expect to restart multiple times before finally beating the game.