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Openai/68f61669-dcb4-8006-9ac5-94599fd4e38d
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==== ⚖️ Struttura brevettuale del CRISPR ==== Il nucleo tecnologico (“sistemi, metodi e composizioni per modificare geni in cellule eucariotiche”) è conteso da due grandi blocchi di diritti: * Broad Institute (MIT/Harvard): detiene i brevetti principali per l’uso di CRISPR-Cas9 in cellule eucariotiche, specialmente negli Stati Uniti e in parte in Europa. * University of California / Berkeley / Jennifer Doudna e Emmanuelle Charpentier: detiene altri brevetti di base sull’invenzione originale (sistema CRISPR-Cas9, soprattutto per uso in vitro e batterico). Entrambi hanno licenziatari commerciali: * Il Broad ha concesso licenze esclusive per usi terapeutici a Editas Medicine, Beam Therapeutics e altre spin-off. * UC/Berkeley, attraverso Caribou Biosciences e CRISPR Therapeutics, gestisce un portafoglio parallelo.
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