Editing Openai/69101fc6-f990-800a-9638-7716259af6c4 (section)

=== (key actives: grape seed extract, pomegranate extract, often cinnamon extract, plus plant protein) ===
* Systolic/diastolic blood pressure ↓ ~1–5 mmHg in people with elevated BP Measure: home BP cuff (morning/evening averages) Why: grape seed proanthocyanidins improve endothelial NO availability & vascular tone. ScienceDirect<ref>{{cite web|title=ScienceDirect|url=https://www.sciencedirect.com/science/article/abs/pii/S0002822311005876|publisher=sciencedirect.com|access-date=2025-11-09}}</ref>Taylor & Francis Online<ref>{{cite web|title=Taylor & Francis Online|url=https://www.tandfonline.com/doi/full/10.1080/10942912.2021.1901731|publisher=Taylor & Francis Online|access-date=2025-11-09}}</ref>PMC<ref>{{cite web|title=PMC|url=https://pmc.ncbi.nlm.nih.gov/articles/PMC7922661/|publisher=pmc.ncbi.nlm.nih.gov|access-date=2025-11-09}}</ref>
* Endothelial function (FMD) ↑ ~1–2 absolute % points Measure: brachial artery flow-mediated dilation at a vascular lab Why: pomegranate polyphenols enhance NO signaling and reduce adhesion molecules. PubMed<ref>{{cite web|title=PubMed|url=https://pubmed.ncbi.nlm.nih.gov/40296437/|publisher=pubmed.ncbi.nlm.nih.gov|access-date=2025-11-09}}</ref>PMC<ref>{{cite web|title=PMC|url=https://pmc.ncbi.nlm.nih.gov/articles/PMC11875170/|publisher=pmc.ncbi.nlm.nih.gov|access-date=2025-11-09}}</ref>
* Glycemic control (if insulin-resistant/T2D) HbA1c ↓ ~0.1–0.3 % and FPG modestly ↓ with cinnamon; changes are small/heterogeneous in healthy folks Measure: HbA1c blood test; CGM metrics (mean glucose, time >140 mg/dL) Why: cinnamon may improve insulin signaling and slow gastric emptying. BioMed Central<ref>{{cite web|title=BioMed Central|url=https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-023-01057-2|publisher=BioMed Central|access-date=2025-11-09}}</ref>PubMed<ref>{{cite web|title=PubMed|url=https://pubmed.ncbi.nlm.nih.gov/37818728/|publisher=pubmed.ncbi.nlm.nih.gov|access-date=2025-11-09}}</ref>